Overcoming tumor resistance to chemotherapy drugs has long been a challenge for oncology clinicians and researchers. Now, a new study suggests that blocking a key protein, p300, may force damaged ...

A new study in mice hints at the potential to use tiny particles made with RNA molecules to deliver chemotherapy drugs and other therapies directly to tumors, killing cancer cells without generating ...

Some chemotherapy drugs cause more damage to healthy cells than other chemo options do, a new study finds. The researchers have found four new mutational signatures — patterns of DNA damage left by ...

Complete DPD deficiency markedly impairs 5-FU catabolism, increasing risk of early severe diarrhea, mucositis, neutropenia, ...

Chemotherapy has long been a cornerstone of cancer treatment, saving millions of lives. Stream Los Angeles News for free, 24/7, wherever you are. Drugmakers have poured billions of dollars into ...

Cancer treatment has always been a balancing act—hit the tumor hard enough to kill it, but not so hard that the patient breaks first. For decades, chemotherapy has walked that razor’s edge, saving ...

Sacubitril-valsartan, a common drug combination for heart failure, cuts the risk for cardiomyopathy after chemotherapy in patients who received anthracycline drugs by 77% in the first randomized ...

Most people who undergo chemotherapy do not develop heart failure. However, specific chemotherapy drugs may significantly increase your risk of heart failure and other cardiac problems. Chemotherapy ...

A biologist works on DNA extracted from cancer tissue in Oncompass Medicine's laboratory in Budapest, Hungary, June 2, 2021. Picture taken June 2, 2021. REUTERS/Bernadett Szabo (This is an excerpt of ...

Since the 1950s a chemotherapy drug known as 5-fluorouracil (5-FU) has been used to treat many types of cancer, including blood cancers and cancers of the digestive tract. Doctors have long believed ...

Cancer patients undergoing chemotherapy may soon have a new option to try to keep their hair — a shampoo-like gel that could protect hair from falling out during chemo. Baldness from ...

The first record of chemotherapy to treat cancer came from Yale University in the 1940s. Researchers there realized that the "leukopenic" properties of mustard gas — that is, its ability to destroy ...