Complement activation by antibodies bound to pathogens, tumors, and self antigens is a critical feature of natural immune defense, a number of disease processes, and immunotherapies. How antibodies ...
Autoantibodies that bind with high affinity to proteins of the complement system have been described in patients with systemic lupus erythematosus (SLE), the prototypic systemic autoimmune disease.
Circulating cold-insoluble complexes, observed in 11 of 31 patients with systemic lupus erythematosus (SLE), consisted mainly of immunoglobulin G and the C′lq component of complement and did not ...
Immunoglobulins are found inside all vertebrates and act as the initial detector of any foreign bodies that come into contact with the host organisms’ bodily systems, such as pathogenic bacteria, for ...
PASC, which is otherwise known as long COVID, arises following the recovery from acute infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus responsible for ...