Am J Health Syst Pharm. 2010;67(4):274-279. The objectives of this study were to develop and test an adjustment factor (AF) for estimating aminoglycoside clearance (CL amino) from the Cockcroft–Gault ...
In this issue of the Journal of Clinical Oncology, Takimoto et al 8 report the results of a phase I and pharmacokinetic study of oxaliplatin in 37 adult cancer patients with renal impairment. This ...
The common use of the Cockcroft-Gault equation suggests that it will remain the method of choice for drug dosing in patients with renal impairment. In contrast, the MDRD4 equation is likely to remain ...
Placebo-Controlled Phase III Trial of Immunologic Therapy with Sipuleucel-T (APC8015) in Patients with Metastatic, Asymptomatic Hormone Refractory Prostate Cancer A database of 208 patients with ...
A team of researchers led by the National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN) and Osaka University established a new method to measure glomerular filtration rate (GFR), ...
Malnutrition is common among patients with cystic fibrosis (CF), which could affect creatinine-based calculation of glomerular filtration rate (GFR). Beringer and colleagues have investigated whether ...
Renal function tests are performed to evaluate how well the kidneys are doing their job of filtering out nitrogenous waste from the blood. They involve the measurement of various substances in both ...