Nature

Longevity of rAAV vector and plasmid DNA in blood after intramuscular injection in nonhuman primates: implications for gene doping

The use of performance-enhancing drugs in sports is commonly referred by the term ‘doping’, particularly by those regulatory bodies overseeing sports that have made efforts to fight doping. Through ...
Nature

Simple and effective osteoinductive gene therapy by local injection of a bone morphogenetic protein-2-expressing recombinant adenoviral vector and FK506 mixture in rats

We have previously utilized a human bone morphogenetic protein-2 (BMP-2)-expressing recombinant adenoviral vector (AxCAOBMP-2) for osteoinductive gene therapy in rats. However, immunosuppression is ...
EurekAlert!

Injection of novel gene therapy vector prolonged survival in mouse model of Pompe disease

New Rochelle, NY, August 13, 2018--A new study has shown that a single injection of a novel adeno-associated vector (AAV)-based therapy can result in improved enzyme activ-ity and glycogen clearance ...
ascopubs.org

GLIPR1/RTVP-1 tumor suppressor gene expressed by adenovirus vector as neoadjuvant intraprostatic injection for localized high-risk prostate cancer preceding prostatectomy.

A detailed analysis of von Hippel Lindau (VHL) mutations in sporadic clear cell renal carcinoma (ccRCC), VHL syndrome, and Chuvash polycythaemia. Background: GLIPR1/RTVP-1 is up-regulated by p53 in ...
Business Wire

Recent Cash Injection Boosts VectorBuilder to Unicorn Status

CHICAGO--(BUSINESS WIRE)--Gene delivery technologies are turning into the next big-ticket item globally, as the most recent investment received by VectorBuilder Inc., a global leader in this field, ...
TechCrunch

Malwarebytes lands a $100M cash injection weeks after laying off 125 employees

Cybersecurity giant Malwarebytes has announced it has received a $100 million cash injection from Vector Capital, a private equity firm that invests in established technology businesses. Vector ...