When you interact with the world around you, your experiences are recorded as changes in the connection strengths between neurons in your brain. This process, called synaptic plasticity, alters how ...

In the brain, synaptic plasticity - the ability to change neuronal connections over time - is fundamental to learning and memory. Traditionally, science has focused on nerve cells and their synapses.

How do we learn something new? How do tasks at a new job, lyrics to the latest hit song, or directions to a friend’s house become encoded in our brains? The broad answer is that our brains undergo ...

Shedding light on how the brain fine-tunes its wiring during learning, a new study finds that different dendritic segments of a single neuron follow distinct rules. The findings challenge the idea ...

The brain’s rules seem simple: Fire together, wire together. When groups of neurons activate, they become interconnected. This networking is how we learn, reason, form memories, and adapt to our world ...

How do we learn something new? How do tasks at a new job, lyrics to the latest hit song or directions to a friend's house become encoded in our brains? The broad answer is that our brains undergo ...

Optogenetic climbing fiber activation regulates experience-dependent plasticity in the primary somatosensory cortex of mice, suggesting a role of the olivo-cerebellum in instructive signaling across ...

When a new memory forms the brain undergoes physical and functional changes known collectively as a “memory trace.” This memory trace represents the specific patterns of neuronal activity and ...

A) Two-photon image of a basal dendrite of L2/3 neuron loaded with Alexa 594. In this example, the spine is ~40 μm below the surface of the slice. Scale bar, 2 μm. (B) Voltage-clamp traces ...

This advance, led by Professor J. Joshua Yang and his team, doesn’t just simulate the brain’s behavior digitally, it physically recreates the electrochemical process of biological neurons. The new ...