To stay healthy, our cells rely on a self-cleaning mechanism that removes defective or unnecessary components. This process, ...

This is a summary of: Liu. H. et al. Viral RNA blocks circularization to evade host codon usage control. Nature https://doi.org/10.1038/s41586-025-09809-y (2025).

Precision and timing of gene expression is essential for normal biological functions and, when disrupted, can lead to many ...

Researchers at VIB and KU Leuven have identified a molecular process that allows motor neurons to maintain protein production ...

Making proteins for research or therapies often starts with cell-line development. In many applications, genetic engineering is used to optimize a cell line for producing high levels of the intended ...

Viral expression was driven by both cap-dependent and IRES-dependent mechanisms under conditions that mimicked viral infection stress. Reproducibility was high both within cell-type replicates ...

To enhance CAR T therapies, scientists are actively studying TCR signaling and T-cell exhaustion mechanisms to improve CAR T persistence and function. Additionally, there is a growing trend towards ...

SRF is a transcription factor directly controlling the expression of at least 200-300 genes, regulating cell growth, proliferation, apoptosis, and motility, and is indispensable for organ development, ...

Researchers at the Indian Institute of Science (IISc), with collaborators from the Institute of Mathematical Sciences (IMSc), ...

Vitamin C is a key nutritional component in fruits, yet its concentration often changes dramatically as fruits develop.