Scientists from the National University of Singapore (NUS) have developed a biochemical technique that captures fleeting ...

A team of US researchers has gained new insights into how large protein molecules consistently fold themselves into useful shapes. Using a new approach to fluorescence microscopy, Hoi Sung Chung and ...

Chung’s group captured the transition period directly by improving the time resolution of a method called single-molecule ...

How does the cell convert DNA into working proteins? The process of translation can be seen as the decoding of instructions for making proteins, involving mRNA in transcription as well as tRNA. But ...

Proteoforms, the diverse molecular variants of proteins, are key to understanding cellular functions, disease mechanisms, and biomarker discovery in proteomics.

Protein activity can be precisely regulated via subtle changes in temperature using heat-sensitive switches. Underlying this ...

Michael Martynowycz, PhD, assistant professor of structural biology at the Jacobs School of Medicine and Biomedical Sciences, recently described a new technique for solving protein structures in a rec ...

Protein misfolding and aggregation are key features observed in numerous neurodegenerative conditions, such as Alzheimer's and Parkinson's disease. The oligomers formed during the aggregation process ...

Stay up to date on the latest science with Brush Up Summaries. Finally, although transgenic animals and mammalian cell culture systems promote optimal expression due to correct protein modifications, ...

A new study shows that improving your cardiovascular endurance changes your neural chemistry. Fitter individuals release ...

Neurodegenerative disorders such as Alzheimer's disease (AD) are typically diagnosed after irreversible pathology has developed. Aging, the strongest risk factor, drives molecular changes that ...