The adjuvanticity of Q. saponins, like QS-21, depends on several chemical groups to induce pro-inflammatory Th1 immune responses. (a) Q. saponins have two groups critical for their Th1 adjuvanticity: ...
Vaccine adjuvants have evolved significantly since their inception, transitioning from empirical discovery to a more structured approach grounded in rational drug design. The origin of vaccine ...
The Nature Index 2025 Research Leaders — previously known as Annual Tables — reveal the leading institutions and countries/territories in the natural and health sciences, according to their output in ...
Computer-aided drug design (CADD) that combines computational chemistry, molecular modeling, and rational drug design with artificial intelligence (AI) and machine learning is rapidly changing the ...
The Icahn School of Medicine at Mount Sinai launched the AI Small Molecule Drug Discovery Center which was created to integrate AI with traditional drug discovery methods to identify and design new ...
There are about 46,000 organ transplants performed a year in the US; their success is, in considerable measure, due to the pioneering work of Gertrude Elion.
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