Thyrotropin-releasing hormone (TRH) is a small yet highly significant tripeptide consisting of the amino acids pyroglutamate, histidine, and proline. First identified in the hypothalamus, TRH was ...

Regulation of thyroid hormone (TH) levels is a complex multilevel phenomenon. The paraventricular nucleus (PVN) of the hypothalamus (the region of the brain that controls the involuntary nervous ...

Levels of thyroid hormones in serum are tightly regulated by the hypothalamic-pituitary-thyroid axis (Figure 1). Hypothalamic TSH-releasing hormone (TRH) is secreted mainly from the paraventricular ...

New research has revealed that fish embryos actively control their hatching timing through a neurohormone, Thyrotropin-Releasing Hormone (TRH), which triggers the release of enzymes that dissolve the ...

Researchers have uncovered a previously unknown yet crucial role for thyrotropin-releasing hormone (Trh) in zebrafish hatching and reveal how this hormone activates a transient neuroendocrine circuit ...