Explore groundbreaking research on pancreatic cancer treatment that shows promise in inducing complete tumour regression.

Spanish researchers have achieved complete eradication of pancreatic tumors in mice using a novel triple-drug therapy.

In this retrospective study, researchers explored whether reducing osimertinib dose in EGFR-mutated metastatic NSCLC patients who experienced adverse events would worsen survival.

A Northwestern Medicine-led study published in the Journal of Clinical Investigation has uncovered why older individuals with specific genetic mutations face a heightened risk of developing serious ...

In mantle cell lymphoma (MCL), an aggressive form of B-cell non-Hodgkin lymphoma, TP53 mutations are known to affect patients’ prognosis—but questions remain. What does the heterogeneity of TP53 ...

The FDA has granted orphan drug designation (ODD) to LP-284, a next-generation acylfulvene small molecule, for the treatment ...

Someone asked “What is a genetics fact that not a lot of people know?” and people detailed their best bits of info.

A new single-cell profiling technique has mapped pre-malignant gene mutations and their effects in solid tissues for the first time, in a study led by ...

Mutations in the tumor suppressor TP53 are a common cause of cancer, making the altered protein an attractive target for therapeutics. Among them, the Y220C mutation is the ninth most frequent and it ...

Mutations in the tumor suppressor TP53 are a common cause of cancer, making the altered protein an attractive target for therapeutics. Among them, the Y220C mutation is the ninth most frequent and it ...

A major investigation has revealed that a sperm donor carrying a dangerous genetic mutation – one that dramatically increases cancer risk – fathered at least 197 children across Europe over a 17-year ...