Rapamycin, mTOR, and Your Genes
Rapamycin, mTOR, and Your Genes
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The Story of TOR (Target of Rapamycin) • iBiology
The Story of TOR (Target of Rapamycin) • iBiology
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Rob Bozada, FRSC on Instagram: "mTOR (mechanistic Target of Rapamycin) is a central regulator of muscle growth and protein synthesis. Some highlights as far as muscle physiology and gene expression are concerned are as follows: 💪🏼Muscle Physiology: * mTORC1, the active complex in muscle, is triggered by: * Mechanical tension (resistance training) * Amino acids (especially leucine) * Insulin and IGF-1 signaling * Once activated, mTORC1 promotes protein synthesis by stimulating: * p70S6 kinase (
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